great tiredness

She knew she should keep running, but intense fatigue and weariness overtook her. 她知道她应该继续奔跑，但极度的疲劳和乏累向她袭来。

30 hours or more of intense physical training might induce some stress or weariness. 30小时或更长时间的高强度体能训练可能会引起压力或疲劳。

the state of being bored with something because you have experienced too much of it

I must admit a certain weariness when reading those passages. 我必须承认阅读那些段落让我感到厌倦。

As soon as they began to talk, he shut his eyes and expressed weariness and indifference. 他们一开始说话，他就闭上眼睛表示他的厌倦和漠不关心。