(especially of a power thought to be greater than ordinary people) to decide or fix what will happen in a way that cannot be changed or controlled

[ + to infinitive ] Illness and suffering seemed (to be) preordained to be her lot. 看来她命中注定了要遭受疾病和苦难。

His life seems to have followed a preordained path/direction. 他的人生似乎遵循着冥冥中业已注定的轨迹／方向前行。