to leave or go away; used especially as a rude way of telling someone to go away

Everyone just pissed off and left me to clean up. 大家都溜走了，留下我一个人来打扫。

Why don't you just piss off - you've caused enough problems already! 你为什么不滚开呢——你惹的麻烦已经够多了！

to annoy someone

He never helps with the housework and it's starting to piss me off. 他从不帮着做家务，这开始让我恼火了。