out of control

Things got a little out of hand at the party and three windows were broken. 聚会的场面有点失控，有3扇窗户被打破了。

He went to see his doctor because he felt his drinking was getting out of hand. 他去见了医生，因为觉得自己的酗酒问题有点失控。

If you refuse something out of hand, you refuse it completely without thinking about or discussing it.

Moving to London is certainly a possibility - I wouldn't dismiss it out of hand. 搬到伦敦去当然也是一种可能的选择——我不会断然拒绝考虑。