(an organization or group that has) complete control of something, especially an area of business, so that others have no share

The government is determined to protect its tobacco monopoly. 政府下决心保护其烟草专卖权。

Is Microsoft a monopoly? 微软是垄断企业吗？

The drafting of a new constitution cannot be a monopoly of the white minority regime (= other people should do it too). 新宪法的起草不能由占人口少数的白人政权垄断。

He does not have a/the monopoly on (= he is not the only one who has) good looks. 长得好看的不止他一个。