to touch or hold someone roughly and with force, often when taking them somewhere

There were complaints that the police had manhandled some of the demonstrators. 有人投诉警察粗暴对待一些示威者。

to move something using the physical strength of the body

Several pieces of heavy equipment had to be manhandled into the lorry. 几件沉重的设备必须由人力搬上卡车。