the condition of being alone, especially when this makes you feel unhappy

The prisoner had been kept in isolation for three days. 这个犯人已被隔离3天了。

After all the visitors had left, she experienced a feeling of complete isolation. 所有的客人离开后，她有一种异常孤独的感觉。

the fact that something is separate and not connected to other things

I can't think about it in isolation (= separately) - I need some examples of the problem. 我无法孤立地考虑这个问题——我需要一些例子。