the feeling of being annoyed, especially because you can do nothing to solve a problem

There is growing exasperation within the government at the failure of these policies to reduce unemployment. 由于这些减少失业的政策不能奏效，政府内部越来越多的人感到懊恼。

After ten hours of fruitless negotiations, he stormed out of the meeting in exasperation. 经过10个小时徒劳无功的漫长谈判，他愤然冲出会场。