a period when you are estranged from someone (= no longer friendly with them), or the fact of no longer being friendly

Their reunion followed a long estrangement. 他们的重逢发生在长期的疏远之后。

He talked about his estrangement from his family. 他谈到了他与家人的疏远。

a feeling that you do not understand someone or something, or do not have any connection with him, her, or it

College athletes share a feeling of estrangement from the other students. 大学运动员与其他学生有一种隔阂的感觉。