A desolate place is empty and not attractive, with no people or nothing pleasant in it.

The house stood in a bleak and desolate landscape. 那所房子坐落在萧瑟荒凉的原野上。

extremely sad and feeling alone

She felt desolate when her best friend moved away. 她最亲密的朋友搬走了，她感到有些伤心寂寞。