to make someone extremely tired

Walking around a museum all day really wears you out. 整天在博物馆里走来走去，真的让人筋疲力尽。

to use something so much that it is damaged and cannot be used any more, or to become damaged in this way

Moving parts in engines wear out much more quickly than stationary parts. 引擎中的运动部件比固定部件磨损得要快得多。