a person who is able to deal with difficult situations and not be easily defeated, frightened, or upset

He said his wife is a tough cookie, a breast cancer survivor who battled the disease for nearly ten years. 他说，他妻子是个坚强的人，她在与乳腺癌斗争了近十年后存活了下来。

And let me tell you something, he's one tough cookie—so be prepared. 听我说，他是一个很难对付的人，所以你要做好准备。