making someone unable to think clearly, usually because they are extremely tired or bored, or have taken drugs

stupefying heat/noise 令人窒息的高温/令人无法思考的噪音

He was sedated by the stupefying drug Lorazepam. 使用了镇静剂劳拉西泮让他昏睡。

very surprising or shocking

stupefying arrogance 令人震惊的傲慢

I find it stupefying that anyone would want to harm a baby. 我觉得很震惊怎么会有人会想去伤害一个婴儿。