to start on a long or difficult journey in a determined way

In heavy rain, we struck out across the valley. 我们在大雨中毅然动身穿过峡谷。

She struck out for the opposite bank. 她奋力向对岸游去。

to start doing something new, independently of other people

After working for her father for ten years, she felt it was time to strike out on her own. 她在为父亲工作了10年之后，感觉到是该自己独立开创一番事业的时候了。

to be unsuccessful

I really struck out with her - she wouldn't even kiss me good night. 我确实把她得罪了——她连吻我道声晚安都不肯。

to fail three times to hit the ball successfully in baseball and therefore to lose one of your team's chances to score, or to cause someone to do this

The pitcher struck out all three batters in the ninth inning and saved the game. 投手在第9局使两名击球手三击不中出局，挽救了比赛。