the act of telling your employer that you are leaving your job

There have been calls for his resignation. 一直有呼声要求他辞职。

I handed in/gave in/sent in my resignation this morning. 我今天上午提交了辞职信。

a sad feeling of accepting something that you do not like because you cannot easily change it

They received the news with resignation. 消息传来，他们听天由命接受了一切。